A 501(c)(3) charity · Since 1996

Striving to cure spinal tumors, in Brian's memory

The Brian D. Silber Memorial Fund supports spinal tumor research, clinical services, and educational programs. It was Brian's hope that his fund would improve the lives of spinal tumor patients and someday help to eradicate spinal tumors.

Brian D. Silber
Saturday, September 20, 2026 · Charles River Esplanade, Boston

Walk with Brian's Team at the Cancer 5K

This year the Brian D. Silber Memorial Fund is fielding a team at the Mass General Brigham Eversource Cancer 5K Run-Walk. Every step supports spinal tumor research, care, and education — join us, fundraise with us, or cheer us on.

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$2.5M+
Raised since 1996 for spinal tumor research, care & education.
$100M+
In follow-on research grants seeded by our early funding.
18
Brian D. Silber Lectures held in the Ether Dome at MGH.
1st
Multidisciplinary spine tumor clinic of its kind, founded at MGH.
News & Updates
Update
Research

Cutting-edge research underway at the Silber Clinic

Work on spinal cord tumor diagnosis and immunotherapy continues at the Brian D. Silber Spine Tumor Clinic at MGH — thanks to our generous donors.

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Recap
Education

Dr. C. Rory Goodwin delivers the 18th Silber Lecture

The Duke spinal oncology director delivered the 18th Brian D. Silber Lecture at MGH on spine tumor treatment decision-making.

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Community
Community

Sunshine and community for the 5K in Boston

Brian's team joined the Mass General Brigham Eversource Cancer 5K Run-Walk on the Charles River Esplanade to support Brian's Fund and cancer care.

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What your gift supports

Three ways Brian's Fund makes a difference for spinal tumor patients

Research

Seed money for early-stage research — funding the projects that lead to major scientific advances. In effect, seed money saves lives.

Clinical Care

Establishing and sustaining the Brian D. Silber Spine Tumor Clinic at Massachusetts General Hospital — the first of its kind.

Education

The annual Brian D. Silber Lecture and symposia bring leading experts together to share advances in spinal tumor care.

Brian on the steps at Tufts University, 1990
Brian's Story

A life of warmth, generosity, and quiet commitment

Brian David Silber grew up in Peabody, Massachusetts, graduated with honors from Tufts University, and was a rising sales executive and accomplished athlete. Even during his illness, he would awaken at five o'clock to serve breakfast to homeless families. Throughout his life, Brian made a difference in the lives of others.

"I've learned that people will forget what you said, people will forget what you did, but people will never forget how you made them feel."

— Maya Angelou, a quote that reminds us of Brian
Read Brian's full story
Meet the researchers

Dr. Arnab Chakravarti

Dr. Chakravarti was the first MGH researcher to receive a grant from Brian's Fund to support spinal cord tumor research. His story shows how our seed money shapes careers and breakthroughs — turning early support into decades of impact.

See what we've accomplished

Join us in perpetuating Brian's dream

Working together we can truly make a difference in the lives of spinal tumor patients and their families.